Laquinimod is an orally-available. quinolinone-based, broad spectrum immunomodulator with anti-inflammatory activity, most likely by effecting a T-helper cell 1 to 2 cytokine shift. [1] Additionally it reduces antigen presentation and the effect on migration of T-cells. Laquinimod is also believed to provide a neuroprotective effect and may have application to relapsing-remitting multiple sclerosis (RRMS). [2]In animal models for multiple sclerosis, Laquinimod reversed established relapsing remitting experimental autoimmune encephalomyelitis (RR EAE) and was associated with reduced CNS inflammation, decreased Th1 and Th17 responses, and an increase in regulatory T cells. [3]

Technical information:

Shipping Condition: The product is shipped in a glass vial at ambient temperature.Storage condition: For longer shelf life, store solid powder at 4^oC desiccated, or store DMSO solution at -20^oC.

Reference:

Other Information:

Product Specification (pdf) MSDS (pdf) Certificate of Analysis is available upon request.

Cellagen利用广泛的研究以及我们在干细胞生物学，药物化学和产品开发方面的专业知识，Cellagen长期以来一直为专业OEM产品提供世界领先的公司，为一线干细胞研究奠定了基础。

现在，Cellagen扩展了其最佳产品系列，并直接向研究界提供。Cellagen与世界领先的科学家有着密切的联系，并且始终认识到高标准科学研究的未满足需求。