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主营类目:SR1分子,干细胞化合物、实验仪器、试剂、生长因子等
℡ 4000-520-616
℡ 4000-520-616
Cellagen/Categories/2 mg (10 mM solution in DMSO)/C4412-2s
产品编号:C4412-2s
市  场 价:¥3180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$159.00
品      牌: Cellagen
公      司:Cellagen Technology LLC
公司分类:
Cellagen/Categories/2 mg (10 mM solution in DMSO)/C4412-2s
商品介绍

Hh-Ag1.5 is a small-molecule chemical agonist of Smoothened (Smo) receptor and is an activator of sonic hedgehog (Shh) signaling. It is derived from an initial synthetic hit compound "Hh-Ag1.1", and optimized to achieve the activity IC50 = 1 nM for agonist activity.


Technical information:

Chemical Formula: C28H26N3OS
CAS #: 612542-14-0
Molecular Weight: 526.04
Purity: >98%
Appearance: Yellow solid
Chemical Name: 3-chloro-4,7-difluoro-N-(4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide
Solubility: Up to 50 mM in DMSO

Shipping Condition: The product is shipped in a glass vial at ambient temperature.Storage: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.


Reference:

1. The Hedgehog Signaling Pathway as a Target for Anticancer Drug Discovery. Borzillo and Lippa. Current Topics in Medicinal Chemistry 2005, (5), 147-157.
2. Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists. Frank-Kamenetsky et. al. Journal of Biology 2002 (1): 10.2-10.19.

Other Information:

Product Specification (pdf)MSDS (pdf)

品牌介绍

Cellagen利用广泛的研究以及我们在干细胞生物学,药物化学和产品开发方面的专业知识,Cellagen长期以来一直为专业OEM产品提供世界领先的公司,为一线干细胞研究奠定了基础。

现在,Cellagen扩展了其最佳产品系列,并直接向研究界提供。Cellagen与世界领先的科学家有着密切的联系,并且始终认识到高标准科学研究的未满足需求。


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