Zearalenoneisaheat-resistantmycotoxinproducedbyfungiinfoodandanimalfeeds[1].ItactsasanestrogenreceptoragoNISTandcancausehormonaleffectsinanimalspeciessuchasthepig[2].EvidenceforZearalenoneeffectshavebeenobservedinawidevarietyofanimals.TheassociationbetweenZearalenoneexposureandhumandiseasesremainsspeculativeatpresent;ithasbeenconsideredasapossIBLecausativeagentinoutbreaksofprecociouspubertalchangesinyoungchildrenandhasbeensuggestedtohaveapossibleinvolvementinhumancervicalcancer.[3,4]
Technicalinformation:
ChemicalFormula: | C18H22O5 | |
CAS#: | 17924-93-4 | |
MolecularWeight: | 318.36 | |
Purity: | >98% | |
Appearance: | Off-white | |
ChemicalName: | (3S,?11E)-?3,?4,?5,?6,?9,?10-?hexahydro-?14,?16-?dihydroxy-?3-?methyl-?1H-?2-?benzoxacyclotetradecin-?1,?7(8H)-?dione | |
Solubility: | Upto50mMinDMSO | |
Synonyms: | Zearalenone,MycotoxinF2,FES,Zenone,ToxinF2 |
ShippingCondition:Theproductisshippedinaglassvialatambienttemperature.
Storagecondition:Forlongershelflife,storesolidpowderorDMSOsolutionat-20oCdesiccated.
Reference:
1. | ZinedineA,etal.Reviewonthetoxicity,occurrence,metabolism,detoxification,regulationsandintakeofzearalenone:Anoestrogenicmycotoxin.FoodChemToxicol,2007;45:1-18PubmedID:17045381 |
2. | TiemannU.andDänickeS.Invivoandinvitroeffectsofthemycotoxinszearalenoneanddeoxynivalenolondifferentnon-reproductiveandreproductiveorgansinfemalepigs:Areview.FoodAdditContam,2007;24:306-314PubmedID:17364934 |
3. | CaloniF.andCortinovisC.Effectsoffusariotoxinsintheequinespecies.VetJ,2010;186:157-161PubmedID:19837621 |
4. | MassartF.andSaggeseG.Oestrogenicmycotoxinexposuresandprecociouspubertaldevelopment.IntJAndrol,2010;33:369-376PubmedID:17364934 |
Cellagen利用广泛的研究以及我们在干细胞生物学,药物化学和产品开发方面的专业知识,Cellagen长期以来一直为专业OEM产品提供世界领先的公司,为一线干细胞研究奠定了基础。
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